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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a85b2c53d4df63a8121c71145a6b59a3388b54176af6a156fb147230ec7357c9' 
  AND token = 'XOo/Qu2M7iutEtv1qfGD9D0aDDS4/9OjeNjHRS9MIik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}