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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '552c4c850fc2fe81baae55c7e8e21e56db4732642c765e7e514d20d729ad7f16' 
  AND token = '27n7KgJiT/MRdmZSE7uZSvWrpxwMmh96GCGproffSHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}