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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a222115a386033490c9f71a545566dfccf1df998bdfda04d6a9fd569e30ac06' 
  AND token = 'IH4vqEXE0+vH6Ux6kLP/4B4YYjpAFdjqNpbIXi99KOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}