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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eb54a58558087c7c4b6c45b45fa5e2d4a9e14f4752785a738fcbb6a24a5015b' 
  AND token = 'zPxxQYqs636UhGEaDR1OtsoHZxHOHJupW2FctLGhrJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}