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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b530aa486646b43045946f8a6ea8cb98347ab3cfab126a3d0c74bf74f232a394' 
  AND token = 'So4/1LFNCsD6k5uj1Wwt2mfeTtXa10Hb0iY8c2HcYgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}