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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ceed34d91884c94852653ca121365c60dd0a74f73c979adf0d6d1b03284b487' 
  AND token = 'IoQQ8eJFCAQH8yzRBw5t81zF3YWi6Mcadzl2FDUENsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}