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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6efd670891890563d09496955595e8668bd7296b9e9da5b2ee9707fc30a154a9' 
  AND token = 'FHHHW/TmdMVBlqS8nqGlcQYkHEoRh2KXW9HeRVek5SU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}