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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '736302d43561016aef2a33975dda8553a32482d78bdb2bd04cc7df3afaae589c' 
  AND token = '8cSK71z4LBiAuaf58bYRYISqJviufEx+6aSJCOPKkak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}