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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abc1d2b08dbe5694bb63a7f54dcbb0edc793eac7bd583658956256e898ad4b76' 
  AND token = 'ppnA90kNbbFbyqMv7Nd1JB8O4Z7qXWC0vrcIhNIL0/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}