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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf287c8b9df79a6f223336b926165ab6d8eba75bf3f1256c5eaba9bcaf3b3e52' 
  AND token = '/c9s80hAIYvrWWWv7fj4v2/o/GrQ93zlNtyNSde4Xz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}