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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c571566d678665df022b36cb764387e333d6c62c005f9e795b27c86f9f83f0' 
  AND token = 'PV1lmJue4aS8OJ2NqF5/fhrewbiJDXnQXZF9RAyqX8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}