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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ce7333942b7b7552437ba70b906d1bc3dc5b1f3c0177cc5a02f7daf08d95afc' 
  AND token = 'guQ1VFUBChkpPqu7+cj9d9tFlBF6vFAuwRzPls9F47g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}