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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d4957eb06b134e9323afc43370b71f3dd017ac23a0429e0f18509fab86db0d' 
  AND token = '4i3oE7068SJB2so3zgVyfHkO10XGUOfvztNzTondaWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}