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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '075046cf98cfd0f165af961ff850d3c4155f0a8d98096493bbf341b8debae59f' 
  AND token = '6FIEa/zRyPvArtO/zO2auxX5WhTCoCXuL5bGf9L1Xzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}