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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8775c5e2dddb3d25cceeab4817c5bb4725a2988489c4c105cfca74c34826af19' 
  AND token = 'DlqLWA3puMfscwjqRMMAWwu9jdOATCTSq71XVfBHxQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}