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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac1a968b1aa89d265099b5c2c3266b875b753d40a021b64d38c93ff82eec494a' 
  AND token = 'VrCUkdknowJQEbssK+6EjeZkakZI1aZ75wa2SJJVT9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}