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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ace314efc1590ee5569ab3091ea2fce20ef9618cd60a84301d48853029effa2' 
  AND token = '3RTOyyxE07937RIDaSdgQY8z/F7Z7kHImWWoxD5tJFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}