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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e95cf7f15062944f0b199d25220380570dd74099587b7cc9b1a785ade37272c' 
  AND token = 'b81UrWBOgbac7GBhuRF2wmDjRVbjr6XLVrUxzGFkGvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}