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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e1ab2d99e1c5fc93358a8fe6bda4b87e4fb735075ff509be43fae41431f21f1' 
  AND token = 'QkbS/JaJ7bvnvTzi3uHcMkkhc9Zjni3ssDyUJqB6OUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}