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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab374157049656c09c260686796ac05c7b19ebb65d087199063d74750e6b9b1c' 
  AND token = 'ek3SDBMd86D9JGOt/nvMT4DM+RSkeoQl1Rz/M9OdOwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}