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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387ca57832b60c67e3cacf0c02976a92c38ed6ab433afae1bc1eb2f9ab3ebdcd' 
  AND token = 't821u6eSnfQ25g2DfO+jObGpRKDkXu3E01EOnOHLgp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}