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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e449d40e3838efd2152ce641b03e07b31ad8ae180615eec6a9e81b822dd1b9cd' 
  AND token = 'UA27+LqU6JqOFh91q85b7/u+3fcPtA0XU0C6YkLP98k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}