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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4d8916d12210653da1481b863c09db5939f5e62d783c4dee380fc45219244c8' 
  AND token = 'GB2MDH8VmxVkXtFvwreWGMVKkKUknfz3sm5Na/NLii8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}