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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac22cd918864a89ecb45abf769df35f413658e813df38a85c50b04bb7eade245' 
  AND token = 'Q2p+qB0i7KWP429TjXHwPnAbY1b1+w2JyZu0TwqcAG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}