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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8b4b99eaa522a82a48a9ed84a6677c6a81e3b62ec1211155716458c0eb79fa7' 
  AND token = 'qYCqSkh+Xa+V0smO/gBcGXnU7Po6hu5Y26EncXzFiz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}