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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d915dd142606d51aa2e62349cbca185706324b83e55b9c2ded949eecb0e098' 
  AND token = 'ZEW2Zvl1+//RTQeGSTzlYGH3vB1cEttF8+O1427MyDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}