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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7003d7bed99d466bc2fd14695a7329c19cb2c87aa6e185b0504e3fb47c83ae80' 
  AND token = 'vpMcwkWCLeeLQsn2g/KDqOAGc3aDsxi9Ssn8qlw/BFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}