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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f29bab6f8eb302477d3ab34fd00cf177aa14c4a7ad0bde0de0db765ce2c5b89c' 
  AND token = 'Vru6Nj/OXi6otb/IEA+Qn/Mz3C5QDlFb3pKoTRWsiVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}