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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16bfbcd1d17f4c71a5b5be2a406ab79776652768c7759cd6073dfef33c42452c' 
  AND token = 'jvJhNtDmWcCr/3O1eZiej/CYsB57uoqRdxATOrkYtHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}