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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0714b4ce489d66d36c81a3269af750813974dd37c1c55a0260b26f471096877' 
  AND token = 'U+H4wgRm5eUvAnUzJsfY91x2lcdxAYAxWocDGlx//4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}