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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17cf5904d604c70489e0839b18804de7c9c634ee2ec44be4e148ab41a234b5cf' 
  AND token = 'uveJeE1pDrt4yW7V0FxITq5KpFlGRIQzxN6yJxHX3E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}