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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a59fc4e68b30a24f2b1a2eba9dc15a0d1b4aaef219f213cafa259673106e214' 
  AND token = '9SHn829WP3/qBH9czxKRDC7D7FEYD3JPjaEtGRQAt4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}