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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29741f33316c4a703f26a665c31790efb885d1065cbbd6b8c0167c9b21768938' 
  AND token = 'yeKMdUOUUvKmcdYGcfmJkhgCTaoZYCJk5qCMSbFQpLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}