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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b78cd5111f43119db5d4abda6b48a9b439a7c46bf125e06b3ec7809277a61a5' 
  AND token = 'OyqzynlK1+9zWdARRADlvAaaVIN87z4hh8sqj9nHZ78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}