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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '260acca44e6fac1a55cd480d4cef96cd7ed321eed4114d18d6fd6532b25195be' 
  AND token = '+jCbalO7IetJMhA41992s4SLCMntsdOVB7NfRmxTHRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}