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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef9a031fa142bcc14d2f6aebc95bdf5dbe5ab5afb2c3283cf1e4127828134b11' 
  AND token = '5l7TWmcHviGpqYtNFzQ4PGB5uGW9xHiO1MaWkcjvRqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}