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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b28ee1d44903ffad6abd0a3b300b18b76b26a42f716774bd06adb7b9f4c0173' 
  AND token = '+5Ih1dmSyWoIOaQEBsCLaLmpZlS9gA71RvYBqOsQWRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}