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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389fd9a4e380438e081040eac632be84ee8b85a2376da31a8051c3e18f042a51' 
  AND token = 'WBuFgne2yFpMVPB/UVvv7kmOK051xDMw6K/3ddXP/dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}