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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef8355d1c54436b9e8154a310bb2d06f4c8c0bc09dca8e07c90aa88f2b2c8cbb' 
  AND token = 'hfEx/mTy4YpRhM1wWh2Dm6B8VblZeADAWbSZUgWkrC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}