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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '046419437abad5e1b7880397f54bb6e8d4eca691c89410f07918d31cec1d177c' 
  AND token = 'uikykihRr6iE4GJle0XXQPRFs2xL4z12g046NoJ6FlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}