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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14b7410e6a528b5d451cec15cfee33e3d4a1b51eb672b60bb5a8b5d013b2c10' 
  AND token = 'bYk+VDo0KvHLAxIV1gt9pj4Lf50gCg8NsdYqsIV8ixw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}