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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4730133d86880811ac5343c7d38b636e253c6ce8ef9dbc132b8ff1ea23e39fbb' 
  AND token = 'dFNDKI9et/GZLgYyGWlziKvaN1ezBnQ/ASmHUfN6cK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}