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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42dd800f7f924f1bcaa97c42c46e03c7e584f296da7f403312a766f39dc105e1' 
  AND token = 'EBD7ZQIqq5DdR3Gf3GMag//9uyfQ5KfOu642zvQYfdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}