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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea5801ca5fcc34d4a83506c65f399a5bcefd0b37bbaae3e16eda7eb07f6cd70' 
  AND token = 'XrAOBMjKsWTRRQUXKvfCc70fACfEAfoYP9X6CJXCkzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}