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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29a2f920f6d7834a95c0caa471bfc495dd07631e3fe01194e1d164064e8641a8' 
  AND token = 'Z0GtTNMVirAc4L/QOkfXBFDknK7rNt6RLLTT+u29GTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}