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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8665309f49b7d3425a54c59fee8590005f7187dee76d3814d267a7fded901531' 
  AND token = 'VbBAX1Ndd+iZfEQQ0PfPIeA0HpdcyJ8Vk/xKigxMD8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}