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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9953b1f48cbe4fef227ebb0f4238a7697b8a94dbaef980337c31c93c19b350db' 
  AND token = 'zRtodP/CLm/ffmSMtAPN6KO4AHY/SY+sj7MRwJSWJFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}