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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd241eb4ebdf25d27aa78debee977344573ee379ab206f4e5dfa74f09c43e4c52' 
  AND token = 'bMH+dBvq4HAhqIQDmLXyykEz9m6/GxcMj0uhfj8i7g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}