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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40e8c85fc195fe21789f85640351920f207368b00508c9eb96ecca7ff685eb46' 
  AND token = 'f9oNZKDil2bZmGfUp/iGU6/VJQNKjkoEI0HMNWnUYK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}