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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '771804d425fce17491ad4d83bfc0c6da7d6c9f1c4440000e4107de732c8b6948' 
  AND token = 'e15+PNYpCCBW4F1bzWRXz23602nrWqjfCc3aBhbIvJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}